Plague, Sickness and Disease

Games involving Disease, be it a core mechanic or a good bit of story, it's always terribly interesting playing a game with it involved.

PATHOLOGIC MY NIGGA

Pathologic or you can play Plague Inc. and mess around with stuff.

Is the name of the game to prevent or spread the course of disease?

Prevent as best you can

Prevent, futilely.

Preventing the inevitable, then go into a mushroom trance and go insane, several ways to do it too.

The first chapter of the main campaign in NWN is all about this. too bad it sucks

Mushroom trance? Sure you're not thinking of Darkwood user? OP, go play Darkwood too

They're point and click flash games, but Morbid 1 and 2 take place during the times of the black death.It turns out vampires were responsible for it.