Nope, and there's still bugs here and there, but it's still a pretty good game.
Main bug I can think of is that worshipping Kysul prevents you from going below a certain depth, when that's only supposed to happen if he's angry with you, if I remember correctly. Still, you can wizard mode past it.
Nethack is an oldie but still pretty good. Featuring a class, race, and alignment system, it's basically an expansion on Rogue in every way, and has become famous for how the developers programmed outcomes for even the most unexpected of internal interactions. It's become more or less the standard against which many roguelikes are measured.
ADoM is notable for having an overworld with a variety of dungeons and peaceful settlements, as well as a rudimentary mission system (some of which are thoroughly infamous). Its setting and effective game mechanics would become the foundation of similar games later on, such as Elona.
Dungeon Crawl: Stone Soup is a newer roguelike split off of the earlier Dungeon Crawl that was originally an attempt to create a "fair" roguelike that was difficult yet ensured that a clever and prepared player would only ever fail by their own mistakes. While it met with decent success and popularity, later updates have regularly been criticized for bloating and oversimplifying the game.
Cataclysm: Dark Days Ahead was a newer attempt at a post-apocalyptic roguelike largely based off the earlier game Cataclysm. It features an infinitely-generating overworld set in a modern New England that has been consumed by a zombie apocalypse, where the player's main goal is to eke out survival. Popular for the setting and surprisingly detailed game mechanics, lately its updates have come under fire for bloating the game or promoting individual coders' unwanted pet projects.
Incursion: Halls of the Goblin King is a partially-complete single-dungeon roguelike that has since been abandoned by its creator, but nonetheless enjoys decent popularity among those who know of it. Heavily based on D&D 3.5, it nonetheless makes a number of adjustments to various mechanics and effects in order to ease the existing flaws of D&D 3.5 and ensure that all skills can be useful to the player.
I can't speak to the modern form of Caves of Qud, so I'll leave that to someone else.
Elona (and the fan expansion Elona+) is a japanese sandbox roguelike largely based on the mechanics of ADoM, but with a powerful emphasis on the things that a player can do and ways the game can be played. Featuring anything from dungeon crawling to running a museum to genetic experimentation on pets to exploring the user-generated realms of moongates, Elona's strongest point is certainly the sheer quantity of content that it has to offer.