Off the top of my head, games I know of that approach genuinely mature topics with anything resembling tact are
>Drakengard 1 and 3 to a degree
And that's all I can think of. Games are usually fine with copious amounts of violence and death but anything sexual is usually met with hesitance at best.
Logan Long
How many R rated films cover rape, child soldiers, or human trafficking?
Mason Brooks
"Mature themes" will never be properly addressed in games and that's ok. Games are stuff you do when you're on a mental vacation. People prefer to be entertained rather than engaged.
Aaron Baker
...
Jeremiah Johnson
hey I like that movie
Jonathan Johnson
Okay. No need to get defensive.
Chase Bailey
Kojima is a hack
Leo Hill
TAKEN was originally R-rated in Europ right? I think it got edited down to PG-13 for the States.
Easton Evans
but it was a really nice movie and Liam Neeson is a really nice man